Amplification mutation rate:85% Amplification mutation rate:83% Amplification mutation rate:82% Amplification mutation rate:82% Deletion mutation rate:82% Deletion mutation rate:82% Deletion mutation rate:82% Deletion mutation rate:81% Deletion mutation rate:81% Deletion mutation rate:81% Deletion mutation rate:81% Deletion mutation rate:81% Deletion mutation rate:81% Deletion mutation rate:81% Amplification mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Amplification mutation rate:80% Amplification mutation rate:80% Amplification mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Amplification mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Deletion mutation rate:80% Amplification mutation rate:79% Deletion mutation rate:79% Deletion mutation rate:79% Deletion mutation rate:79% Deletion mutation rate:79% Deletion mutation rate:79% Deletion mutation rate:79% Amplification mutation rate:79% Deletion mutation rate:79% Amplification mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Amplification mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Deletion mutation rate:78% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Amplification mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Deletion mutation rate:77% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Amplification mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Deletion mutation rate:76% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Deletion mutation rate:75% Deletion mutation rate:75% Deletion mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Deletion mutation rate:75% Deletion mutation rate:75% Deletion mutation rate:75% Deletion mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:75% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Deletion mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:74% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Amplification mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Deletion mutation rate:73% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Amplification mutation rate:72% Deletion mutation rate:72% Deletion mutation rate:72% Amplification mutation rate:71% Deletion mutation rate:71% Deletion mutation rate:71% Deletion mutation rate:71% Deletion mutation rate:71% Deletion mutation rate:71% Deletion mutation rate:71% Deletion mutation rate:71% Amplification mutation rate:70% Amplification mutation rate:70% Amplification mutation rate:70% Amplification mutation rate:70% Amplification mutation rate:70% Deletion mutation rate:70% Deletion mutation rate:69% Deletion mutation rate:69% Amplification mutation rate:68% Amplification mutation rate:67% Amplification mutation rate:67% Deletion mutation rate:66% Deletion mutation rate:66% Deletion mutation rate:65% Deletion mutation rate:60% Deletion mutation rate:56% Deletion mutation rate:54% Deletion mutation rate:53% Deletion mutation rate:51% Deletion mutation rate:51% Deletion mutation rate:48% Deletion mutation rate:46% Amplification mutation rate:46% Deletion mutation rate:46% Deletion mutation rate:45% Deletion mutation rate:44% Amplification mutation rate:44% Deletion mutation rate:44% Deletion mutation rate:44% Amplification mutation rate:44% Amplification mutation rate:43% Deletion mutation rate:43% Deletion mutation rate:43% Deletion mutation rate:43% Deletion mutation rate:43% Amplification mutation rate:42% Amplification mutation rate:42% Amplification mutation rate:42% Amplification mutation rate:42% Amplification mutation rate:42% Amplification mutation rate:41% Amplification mutation rate:41% Amplification mutation rate:41% Amplification mutation rate:41% Deletion mutation rate:41% Amplification mutation rate:41% Amplification mutation rate:41% Deletion mutation rate:41% Amplification mutation rate:40% Amplification mutation rate:40% Deletion mutation rate:40% Deletion mutation rate:40% Deletion mutation rate:40% Amplification mutation rate:40% Amplification mutation rate:40% Amplification mutation rate:40% Deletion mutation rate:40% Deletion mutation rate:40% Deletion mutation rate:40% Deletion mutation rate:40% Amplification mutation rate:39% Deletion mutation rate:39% Deletion mutation rate:39% Deletion mutation rate:39% Amplification mutation rate:38% Deletion mutation rate:38% Amplification mutation rate:38% Deletion mutation rate:38% Deletion mutation rate:38% Deletion mutation rate:38% Amplification mutation rate:38% Amplification mutation rate:38% Deletion mutation rate:38% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Deletion mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:37% Amplification mutation rate:36% Amplification mutation rate:36% Deletion mutation rate:36% Deletion mutation rate:36% Deletion mutation rate:36% Deletion mutation rate:36% Amplification mutation rate:36% Deletion mutation rate:36% Deletion mutation rate:36% Deletion mutation rate:36% Deletion mutation rate:36% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Deletion mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Amplification mutation rate:35% Deletion mutation rate:35% Deletion mutation rate:35% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Amplification mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Deletion mutation rate:34% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Deletion mutation rate:33% Deletion mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Amplification mutation rate:33% Deletion mutation rate:33% Deletion mutation rate:33% Deletion mutation rate:33% Deletion mutation rate:33% Deletion mutation rate:33% Deletion mutation rate:33% Amplification mutation rate:32% Amplification mutation rate:32% Deletion mutation rate:32% Deletion mutation rate:32% Deletion mutation rate:32% Amplification mutation rate:32% Amplification mutation rate:32% Amplification mutation rate:32% Deletion mutation rate:32% Amplification mutation rate:32% Amplification mutation rate:32% Amplification mutation rate:32% Amplification mutation rate:32% Deletion mutation rate:32% Deletion mutation rate:32% Deletion mutation rate:32% Amplification mutation rate:31% Amplification mutation rate:31% Deletion mutation rate:31% Deletion mutation rate:31% Amplification mutation rate:31% Deletion mutation rate:31% Amplification mutation rate:31% Amplification mutation rate:31% Amplification mutation rate:31% Amplification mutation rate:31% Amplification mutation rate:31% Amplification mutation rate:31% Deletion mutation rate:31% Deletion mutation rate:31% Deletion mutation rate:31% Amplification mutation rate:30% Amplification mutation rate:30% Deletion mutation rate:30% Amplification mutation rate:30% Deletion mutation rate:30% Deletion mutation rate:30% Amplification mutation rate:30% Amplification mutation rate:30% Amplification mutation rate:30% Deletion mutation rate:30% Deletion mutation rate:30% Deletion mutation rate:30% Deletion mutation rate:29% Deletion mutation rate:29% Deletion mutation rate:29% Deletion mutation rate:29% Deletion mutation rate:29% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Amplification mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:28% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Amplification mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:27% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Deletion mutation rate:26% Amplification mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% TP53 mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Deletion mutation rate:25% Amplification mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Deletion mutation rate:24% Amplification mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:23% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Amplification mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Amplification mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Deletion mutation rate:22% Amplification mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Amplification mutation rate:21% Amplification mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Deletion mutation rate:21% Amplification mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Amplification mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% PTEN mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Deletion mutation rate:20% Amplification mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Amplification mutation rate:19% Amplification mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Deletion mutation rate:19% Amplification mutation rate:18% Amplification mutation rate:18% Amplification mutation rate:18% Amplification mutation rate:18% Amplification mutation rate:18% Amplification mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Amplification mutation rate:18% Amplification mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Amplification mutation rate:18% Amplification mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Deletion mutation rate:18% Amplification mutation rate:17% Amplification mutation rate:17% Amplification mutation rate:17% Amplification mutation rate:17% Amplification mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Amplification mutation rate:17% Amplification mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Deletion mutation rate:17% Amplification mutation rate:16% Amplification mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Amplification mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Deletion mutation rate:16% Amplification mutation rate:15% Amplification mutation rate:15% Amplification mutation rate:15% Amplification mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Amplification mutation rate:15% Amplification mutation rate:15% Amplification mutation rate:15% Amplification mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Amplification mutation rate:15% Amplification mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Deletion mutation rate:15% Amplification mutation rate:14% Amplification mutation rate:14% Amplification mutation rate:14% Amplification mutation rate:14% Amplification mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Amplification mutation rate:14% Amplification mutation rate:14% Amplification mutation rate:14% Amplification mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Deletion mutation rate:14% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Amplification mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Deletion mutation rate:13% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% EGFR mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Amplification mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Deletion mutation rate:12% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Amplification mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Deletion mutation rate:11% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Amplification mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Deletion mutation rate:10% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Amplification mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Deletion mutation rate:9% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% NF1 mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Amplification mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Deletion mutation rate:8% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Amplification mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Deletion mutation rate:7% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% RB1 mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Amplification mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Deletion mutation rate:6% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Amplification mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5% Deletion mutation rate:5%